November 15, 2024
11 11 11 AM
The Surreal Life Costars Kim Zolciak & Chet Hanks Fuel Dating Rumors
The View’s Sara Haines Walks Off After Whoopi Goldberg’s NSFW Comment
Caitlin Clark golf score today: Live results for WNBA star at LPGA ‘The Annika’ Pro-Am
How to Build Your Target Fall Capsule Wardrobe
Researchers Develop Novel Framework Leveraging Multi-Omics Data to Advance Environmental Precision Health
Can’t Give Them the World? One of These Luxe Gift Ideas Will Do
Brianna LaPaglia Denies Dave Portnoy Paid $10M for Zach Bryan Tell-All
Moscow targeted as Ukraine and Russia trade huge drone attacks
Ella Emhoff Slams Rumors She Was Hospitalized For a Mental Breakdown
Trump campaign adviser says Ukraine focus must be peace, not territory
Latest Post
The Surreal Life Costars Kim Zolciak & Chet Hanks Fuel Dating Rumors The View’s Sara Haines Walks Off After Whoopi Goldberg’s NSFW Comment Caitlin Clark golf score today: Live results for WNBA star at LPGA ‘The Annika’ Pro-Am How to Build Your Target Fall Capsule Wardrobe Researchers Develop Novel Framework Leveraging Multi-Omics Data to Advance Environmental Precision Health Can’t Give Them the World? One of These Luxe Gift Ideas Will Do Brianna LaPaglia Denies Dave Portnoy Paid $10M for Zach Bryan Tell-All Moscow targeted as Ukraine and Russia trade huge drone attacks Ella Emhoff Slams Rumors She Was Hospitalized For a Mental Breakdown Trump campaign adviser says Ukraine focus must be peace, not territory

$11.3 million NIH Superfund award to address environmental health issues caused by VOCs

Wayne State's Melissa Runge-Morris, M.D. and Carol Miller, Ph.D., have received an $11.3 million award from NIEHS for a new Superfund Research Program. Art by Alexis Wright, WSU student.
Wayne State’s Melissa Runge-Morris, M.D. and Carol Miller, Ph.D., have received an $11.3 million award from NIEHS for a new Superfund Research Program. Art by Alexis Wright, WSU student.

Wayne State to lead multidisciplinary, multiorganization team

Melissa Runge-Morris, M.D.

DETROIT – Wayne State University has received a five-year, approximately $11.3 million award from the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health to create a new Superfund Research Program, the “Center for Leadership in Environmental Awareness and Research (CLEAR).” The Center will be dedicated to understanding and mitigating adverse birth outcomes and serious developmental health problems that have been associated with urban environmental exposure to volatile organic chemcials (VOCs), a special class of pollutant found in the subsurface of post-industrial cities like Detroit.

Carol Miller, Ph.D.

VOCs are a group of aromatic or chlorinated organic compounds that transition to a vapor or gas. They are a source of indoor air contamination in the urban built environment. Commonly encountered VOCs  include benzene, toluene, ethylbenzene, xylene, trichloroethylene and tetrachloroethylene. Nationwide, VOCs pose a potential threat to human health through a process known as “vapor intrusion.” Vapor intrusion occurs when man-made chemicals in the subsurface vaporize, rise through the subsurface, and ultimately migrate into overlying homes and buildings through structural cracks in walls, floors and building foundations. CLEAR will provide new methods for assessment, testing and mitigation to help reduce toxic exposures and improve health outcomes. It will also offer an important training component for Ph.D. students and postdoctoral fellows, providing them with an opportunity for hands-on field and laboratory research, microinternships, and a graduate certificate in urban environmental health.

Headquartered on the Wayne State University campus, CLEAR will focus on Detroit as the principal study site. The CLEAR team consists of engineering and biomedical scientists, educators, and community partners. Detroit has the highest preterm birth rate in the United States. The city also has a very large number of identified sites of environmental contamination (brownfields) with VOCs. The CLEAR team hypothesizes that VOC exposure through vapor intrusion early in life incites inflammatory responses in maternal tissues as well in the developing offspring that reprogram the developing immune system and other critical systems, setting the stage for preterm birth and/or associated adverse health outcomes.

The CLEAR research team is led by  Melissa Runge-Morris, M.D., and Carol Miller, Ph.D., who also co-lead the One Health Initiative at Wayne State University. Physician-scientist Runge-Morris is the director of the Institute of Environmental Health Sciences/Center for Urban Responses to Environmental Stressors (IEHS/CURES) at Wayne State University. Engineer Miller is a professor in the Department of Civil and Environmental Engineering at Wayne State University and director of Healthy Urban Waters, funded by the Fred A. and Barbara M. Erb Family Foundation. The innovative CLEAR program integrates engineering and biomedical approaches to detect, quantify and eradicate the health risks that stem from environmental exposure to VOCs and their mixtures. The research team is made up of 31 faculty in six colleges and schools at Wayne State along with researchers from Henry Ford Health System, Michigan State University, Ann Arbor Technical Services, Inc., North Carolina State University and University of Florida.

“We will have five integrative environmental science and engineering and biomedical research projects that will investigate toxic mechanisms, exposure pathways, biomarkers and strategies to prevent exposures and improve public health outcomes,” said Runge-Morris. “This will include new detection methodologies including phytoscreening – a screening method used to identify bioactive substances in plants. In addition, we will integrate Internet of Things and edge computing for real-time contaminant detection, rapid-response, mitigation and remediation of toxins. We will apply advanced analysis methods and tools to determine the impact of VOC exposures on preterm birth and other adverse health outcomes.”

The CLEAR team recently published new evidence linking preterm birth outcomes in people to VOC pollution in Detroit. The study demonstrated positive associations between VOC exposures and adverse birth outcomes which have been noted in other studies in the United States, Canada, France, Brazil and Spain. The CLEAR team also have found a positive association between VOC exposure and maternal inflammation as well as changes in placental gene expression.

“Detroit has the highest minority population in the Great Lakes region with issues of numerous health and environmental injustices,” said Miller. “These are related to aging infrastructure and prevalent legacy contaminants. With the highest reported rate of preterm births in the U.S., it is critical to examine the etiologic factors that are playing a key role in this public health emergency. This study is critical to researching and developing new methods of assessment, testing and mitigation to reduce toxic exposures and improve health outcomes of our vulnerable community in Detroit as well as many other cities around the U.S. and the world.”

The project number for this National Institute of Environmental Health Sciences award is P42ES030991.

About Wayne State University

Wayne State University is one of the nation’s pre-eminent public research universities in an urban setting. Through its multidisciplinary approach to research and education, and its ongoing collaboration with government, industry and other institutions, the university seeks to enhance economic growth and improve the quality of life in the city of Detroit, state of Michigan and throughout the world. For more information about research at Wayne State University, visit research.wayne.edu.

Assets

46 thoughts on “$11.3 million NIH Superfund award to address environmental health issues caused by VOCs”

  8. viagra online cheap rulide cefadroxil monohydrate adalah obat The troubled starlet stripped her burning pants off during the bizarre incident, the News first reported, and later fled the scene in her signature long blond wig to rinse her fuel drenched dog in the sink of a nearby convenience store

  13. Крупный учебный и научно-исследовательский центр Республики Беларусь. Высшее образование в сфере гуманитарных и естественных наук на 12 факультетах по 35 специальностям первой ступени образования и 22 специальностям второй, 69 специализациям.

  18. I think this is one of the most significant information for me. And i’m glad reading your article. But want to remark on few general things, The site style is perfect, the articles is really nice : D. Good job, cheers

  21. Hi there, just became alert to your blog through Google,
    and found that it is really informative. I’m gonna watch out for brussels.
    I will be grateful if you continue this in future.

    Numerous people will be benefited from your writing.
    Cheers! Escape room lista

  24. Hey there I am so excited I found your site, I really found you by error, while I was searching on Bing for something else, Nonetheless I am here now and would just like to say kudos for a remarkable post and a all round enjoyable blog (I also love the theme/design), I dont have time to look over it all at the minute but I have book-marked it and also added in your RSS feeds, so when I have time I will be back to read a great deal more, Please do keep up the superb jo.

  26. Exceptional post but I was wondering if you could write a litte more on this topic? I’d be very grateful if you could elaborate a little bit more. Thank you!

  40. I blog quite often and I seriously appreciate your information. This great article has truly peaked my interest. I will take a note of your blog and keep checking for new information about once a week. I opted in for your Feed too.

  41. I blog quite often and I seriously appreciate your information. This great article has truly peaked my interest. I will take a note of your blog and keep checking for new information about once a week. I opted in for your Feed too.

  42. I blog quite often and I seriously appreciate your information. This great article has truly peaked my interest. I will take a note of your blog and keep checking for new information about once a week. I opted in for your Feed too.

  43. I blog quite often and I seriously appreciate your information. This great article has truly peaked my interest. I will take a note of your blog and keep checking for new information about once a week. I opted in for your Feed too.

  44. I blog quite often and I seriously appreciate your information. This great article has truly peaked my interest. I will take a note of your blog and keep checking for new information about once a week. I opted in for your Feed too.

  46. Hello there! Do you know if they make any plugins
    to help with Search Engine Optimization? I’m trying to get
    my blog to rank for some targeted keywords but I’m not seeing very
    good success. If you know of any please share.
    Thanks! You can read similar text here: Eco product

Leave a Reply

Your email address will not be published. Required fields are marked *