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Common Consumer Product Chemicals Now Tied to Cardiac Electrical Changes

“Our findings were highly sex-specific,” said Wang. In women, researchers identified an association with longer QRS duration, or contraction of the ventricles, and dysfunction of the electrical impulses of the heart.

“It was particularly pronounced in women with higher body mass indexes,” said Wang. 

In men, researchers found higher exposure to triclocarban (TCC), an antimicrobial agent, led to longer QT intervals in the heart — meaning the heart’s electrical system is taking too long to recharge, a situation that can contribute to heart rhythm dysfunction. TCC has since been banned in the United States.

Wang also pointed out that typical exposure levels alone are unlikely to cause clinically significant heart disease in healthy people. 

“These were not dramatic changes that we observed, but moderate changes to cardiac electrical activity,” he said. “However, they were particularly pronounced in certain subpopulations.” 

He said the altered cardiac activity could exacerbate existing heart disease or arrhythmias in a patient, especially older adults or those with other risk factors.

“Now there are new chemicals out there, so the next step would be to examine these newer environmental chemicals and to focus on their impact on an individual level in those who are predisposed to heart disease,” said Wang.

Click here to read the entire study in Environmental Health.

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